Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.4
USERS' SCORE
Moderately Good
Based on 31 Reviews
7.6
Supplement Facts
Serving Size: 2 Vegetarian Capsules
Amount Per Serving
%DV
Thiamine (vitamin B1) (as thiamine HCl)
100 mg
8333%
Riboflavin (vitamin B2) (as riboflavin and riboflavin 5'-phosphate)
75 mg
5769%
Niacin (as niacinamide and niacin)
100 mg•
625%
Vitamin B6 (as pyridoxine HCl and pyridoxal 5' phosphate)
100 mg
5882%
Folate (as L-5-methyltetrahydrofolate calcium salt)
680 mcg○
170%
Vitamin B12 (as methylcobalamin)
300 mcg
12500%
Biotin
1000 mcg
3333%
Pantothenic acid (as D-calcium pantothenate)
500 mg
10000%
Calcium (as D-calcium pantothenate, dicalcium phosphate)
50 mg
4%
Inositol
100 mg
**
PABA (para-aminobenzoic acid)
50 mg
**
Top Medical Research Studies
9
We explored how vitamin B6 (VB6) supports heart recovery post-heart attack. In our study, we found that VB6 encourages angiogenesis, which is crucial for healing. Through experiments, we noticed that VB6 helps in cell migration and blood vessel formation by activating a specific protein that plays a key role in these processes. Additionally, long-term use of VB6 improved heart function in mice. While these findings are promising, it’s important to note that further research is necessary to fully understand VB6's effects in humans.
Read More
9
We looked into whether vitamin B-6 could help prevent heart failure with preserved ejection fraction (HFpEF) in a mouse model. By using a high-fat diet and other supplements, we created conditions for HFpEF and tested the effects of vitamin B-6 on cardiac function.
The results showed that co-administering vitamin B-6 improved heart function and reduced harmful phenotypic changes in heart macrophages. However, these benefits disappeared in mice lacking a specific protein called DOK3. Overall, vitamin B-6 appears to help mitigate HFpEF by supporting DOK3 signaling and inhibiting detrimental macrophage changes.
The results showed that co-administering vitamin B-6 improved heart function and reduced harmful phenotypic changes in heart macrophages. However, these benefits disappeared in mice lacking a specific protein called DOK3. Overall, vitamin B-6 appears to help mitigate HFpEF by supporting DOK3 signaling and inhibiting detrimental macrophage changes.
Read More
8
We explored the impact of long-term vitamin B1 (VB1) maintenance on heart failure (HF) outcomes through a study involving 88 patients. These patients were divided into three groups based on their VB1 levels: a control group with normal levels, a group receiving short-term supplementation, and a group focused on long-term maintenance of normal levels.
The results showed that those who maintained normal VB1 levels experienced better health outcomes compared to those in the other groups. Our findings indicate that consistent VB1 management could be crucial for enhancing HF therapy and reducing risks of hospitalization and cardiovascular death.
The results showed that those who maintained normal VB1 levels experienced better health outcomes compared to those in the other groups. Our findings indicate that consistent VB1 management could be crucial for enhancing HF therapy and reducing risks of hospitalization and cardiovascular death.
Read More
Most Useful Reviews
9
Reduces stress levels
62 people found this helpful
This vitamin complex has been amazing! After two years of use, I’ve seen improvements in my gut function and skin health, and I’ve become more emotionally stable. It aids in coping with stress, supports the immune system, and enhances overall bodily functions including the cardiovascular system. This B vitamin complex effectively does its job without adverse reactions.
Read More
9
Increased energy
5 people found this helpful
An excellent energy booster! I bought these vitamins for my parents, who often felt fatigued. Recommended by their doctor for heart and brain health, they noticed effects after dinner. They now feel energised and are more active outdoors, describing themselves as "alive" again. I intend to order for myself and my husband!
Read More
9
Overall health
3 people found this helpful
Amazing Bs for heart and brain health! BioActive Complete B-Complex provides all necessary B vitamins, supporting energy production, cellular activity, and skin health. The ingredients are in easily absorbable forms, optimising bodily functions. The quality is outstanding and among the best available.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.4
- All Researches
9
We explored how vitamin B6 (VB6) supports heart recovery post-heart attack. In our study, we found that VB6 encourages angiogenesis, which is crucial for healing. Through experiments, we noticed that VB6 helps in cell migration and blood vessel formation by activating a specific protein that plays a key role in these processes. Additionally, long-term use of VB6 improved heart function in mice. While these findings are promising, it’s important to note that further research is necessary to fully understand VB6's effects in humans.
Read More
9
We looked into whether vitamin B-6 could help prevent heart failure with preserved ejection fraction (HFpEF) in a mouse model. By using a high-fat diet and other supplements, we created conditions for HFpEF and tested the effects of vitamin B-6 on cardiac function.
The results showed that co-administering vitamin B-6 improved heart function and reduced harmful phenotypic changes in heart macrophages. However, these benefits disappeared in mice lacking a specific protein called DOK3. Overall, vitamin B-6 appears to help mitigate HFpEF by supporting DOK3 signaling and inhibiting detrimental macrophage changes.
The results showed that co-administering vitamin B-6 improved heart function and reduced harmful phenotypic changes in heart macrophages. However, these benefits disappeared in mice lacking a specific protein called DOK3. Overall, vitamin B-6 appears to help mitigate HFpEF by supporting DOK3 signaling and inhibiting detrimental macrophage changes.
Read More
8
We investigated how a specific gene variation (MTHFR C677T) influences the outcome for patients with coronary heart disease and hypertension receiving folic acid and enalapril.
Over 540 patients were studied, dividing them into groups that received folic acid or standard treatment.
Our results revealed that patients who took folic acid had better outcomes, including lower rates of cardiovascular events, compared to those who did not. This indicates that folic acid supplementation may enhance treatment success for these high-risk patients.
Over 540 patients were studied, dividing them into groups that received folic acid or standard treatment.
Our results revealed that patients who took folic acid had better outcomes, including lower rates of cardiovascular events, compared to those who did not. This indicates that folic acid supplementation may enhance treatment success for these high-risk patients.
Read More
8
In our exploration of TANGO2-deficiency disorder, we found that cardiac arrhythmias linked to this genetic condition are often resistant to standard treatments.
Using innovative patient-derived stem cell models, we identified that high doses of folate (vitamin B9) can significantly reduce arrhythmias.
Clinical data also indicated that multivitamin and B complex intake may lower the risk of serious heart issues in affected individuals.
This suggests that B vitamins might offer a life-saving strategy for managing dangerous cardiac events in patients with this disorder.
Using innovative patient-derived stem cell models, we identified that high doses of folate (vitamin B9) can significantly reduce arrhythmias.
Clinical data also indicated that multivitamin and B complex intake may lower the risk of serious heart issues in affected individuals.
This suggests that B vitamins might offer a life-saving strategy for managing dangerous cardiac events in patients with this disorder.
Read More
8
We explored the impact of long-term vitamin B1 (VB1) maintenance on heart failure (HF) outcomes through a study involving 88 patients. These patients were divided into three groups based on their VB1 levels: a control group with normal levels, a group receiving short-term supplementation, and a group focused on long-term maintenance of normal levels.
The results showed that those who maintained normal VB1 levels experienced better health outcomes compared to those in the other groups. Our findings indicate that consistent VB1 management could be crucial for enhancing HF therapy and reducing risks of hospitalization and cardiovascular death.
The results showed that those who maintained normal VB1 levels experienced better health outcomes compared to those in the other groups. Our findings indicate that consistent VB1 management could be crucial for enhancing HF therapy and reducing risks of hospitalization and cardiovascular death.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 31 Reviews
7.6
- All Reviews
- Positive Reviews
- Negative Reviews
9
Reduces stress levels
62 people found this helpful
This vitamin complex has been amazing! After two years of use, I’ve seen improvements in my gut function and skin health, and I’ve become more emotionally stable. It aids in coping with stress, supports the immune system, and enhances overall bodily functions including the cardiovascular system. This B vitamin complex effectively does its job without adverse reactions.
Read More
9
Increased energy
5 people found this helpful
An excellent energy booster! I bought these vitamins for my parents, who often felt fatigued. Recommended by their doctor for heart and brain health, they noticed effects after dinner. They now feel energised and are more active outdoors, describing themselves as "alive" again. I intend to order for myself and my husband!
Read More
9
Overall health
3 people found this helpful
Amazing Bs for heart and brain health! BioActive Complete B-Complex provides all necessary B vitamins, supporting energy production, cellular activity, and skin health. The ingredients are in easily absorbable forms, optimising bodily functions. The quality is outstanding and among the best available.
Read More
9
Relieved hand pain
1 people found this helpful
I struggled with pain in my right hand, diagnosed as Arthritis at 33. Despite treatments, I found no relief. However, after taking a B complex recommended by my gynecologist while breastfeeding, I regained cheerfulness. My hair improved, and dryness reduced. A month later, I realised my hand no longer hurt. Now, I recommend this complex to nursing mothers. It's an excellent remedy, just don’t take it on an empty stomach!
Read More
9
Alleviates dizziness
9 people found this helpful
I was suffering from dizziness, dryness, and hair loss, but thankfully within a week of taking this complex, the dizziness and hair loss began to ease significantly.
Read More
Frequently Asked Questions
9
Alleviates dizziness
9 people found this helpful
I was suffering from dizziness, dryness, and hair loss, but thankfully within a week of taking this complex, the dizziness and hair loss began to ease significantly.
9
Relieved hand pain
1 people found this helpful
I struggled with pain in my right hand, diagnosed as Arthritis at 33. Despite treatments, I found no relief. However, after taking a B complex recommended by my gynecologist while breastfeeding, I regained cheerfulness. My hair improved, and dryness reduced. A month later, I realised my hand no longer hurt. Now, I recommend this complex to nursing mothers. It's an excellent remedy, just don’t take it on an empty stomach!
9
Increased energy
5 people found this helpful
An excellent energy booster! I bought these vitamins for my parents, who often felt fatigued. Recommended by their doctor for heart and brain health, they noticed effects after dinner. They now feel energised and are more active outdoors, describing themselves as "alive" again. I intend to order for myself and my husband!
9
Reduces stress levels
62 people found this helpful
This vitamin complex has been amazing! After two years of use, I’ve seen improvements in my gut function and skin health, and I’ve become more emotionally stable. It aids in coping with stress, supports the immune system, and enhances overall bodily functions including the cardiovascular system. This B vitamin complex effectively does its job without adverse reactions.
7.5
Reduces homocysteine
1 people found this helpful
I take this vitamin to reduce homocysteine alongside other supplements. The quality is excellent, with digestible forms of B vitamins that promote nerve cell health and support heart health.
7.5
Supports heart system
1 people found this helpful
I tend to take vitamins from group B regularly, but lately, I've switched to taking them separately, as they tend to be more effective. This manufacturer provides good quality products. I often use ashwagandha and omega 3 from them. It’s important to manage high doses of B6 to avoid issues like polyneuropathy. Overall, this complex supports normal energy metabolism and is beneficial for the heart.
6
Cardiovascular support
7 people found this helpful
This complex provides all essential vitamins that play critical roles in bodily functions. It significantly affects the cardiovascular system and brain health. Vitamin B12 regulates fats and carbohydrates and aids DNA production, while B6 and B1 promote heart health and sleep regulation. Additionally, folic acid elevates serotonin levels, enhancing emotional well-being. This supplement swiftly restores vitamin levels, improving overall health.
6
Prevents heart disease
2 people found this helpful
Vitamin B plays a vital role in regulating metabolism, enhancing immune and nervous system functions, and supports cell growth and division, notably in red blood cell production, which helps prevent anaemia and reduces the chances of heart disease. A deficiency in Vitamin B can lead to fatigue, weakness, and severe health issues.
9
We explored how vitamin B6 (VB6) supports heart recovery post-heart attack. In our study, we found that VB6 encourages angiogenesis, which is crucial for healing. Through experiments, we noticed that VB6 helps in cell migration and blood vessel formation by activating a specific protein that plays a key role in these processes. Additionally, long-term use of VB6 improved heart function in mice. While these findings are promising, it’s important to note that further research is necessary to fully understand VB6's effects in humans.
8
We investigated how a specific gene variation (MTHFR C677T) influences the outcome for patients with coronary heart disease and hypertension receiving folic acid and enalapril.
Over 540 patients were studied, dividing them into groups that received folic acid or standard treatment.
Our results revealed that patients who took folic acid had better outcomes, including lower rates of cardiovascular events, compared to those who did not. This indicates that folic acid supplementation may enhance treatment success for these high-risk patients.
Over 540 patients were studied, dividing them into groups that received folic acid or standard treatment.
Our results revealed that patients who took folic acid had better outcomes, including lower rates of cardiovascular events, compared to those who did not. This indicates that folic acid supplementation may enhance treatment success for these high-risk patients.
8
We explored the impact of long-term vitamin B1 (VB1) maintenance on heart failure (HF) outcomes through a study involving 88 patients. These patients were divided into three groups based on their VB1 levels: a control group with normal levels, a group receiving short-term supplementation, and a group focused on long-term maintenance of normal levels.
The results showed that those who maintained normal VB1 levels experienced better health outcomes compared to those in the other groups. Our findings indicate that consistent VB1 management could be crucial for enhancing HF therapy and reducing risks of hospitalization and cardiovascular death.
The results showed that those who maintained normal VB1 levels experienced better health outcomes compared to those in the other groups. Our findings indicate that consistent VB1 management could be crucial for enhancing HF therapy and reducing risks of hospitalization and cardiovascular death.
References
- Wang XQ, Yin S, Wang QW, Bai WW, Tan RH, et al. Vitamin B6 allosterically activates AMPK to promote postischemic angiogenesis in mice. Eur J Pharmacol. 2025;993:177413. 10.1016/j.ejphar.2025.177413
- Ma L, Zeng L, Wang X. MTHFR C677T gene polymorphism in patients with coronary heart disease and hypertension treated with enalapril and folic acid: implications for prognosis. Cell Mol Biol (Noisy-le-grand). 2024;70:142. 10.14715/cmb/2024.70.9.20
- Song JW, Zhang ZS, Chen L, Wang QW, Xu JY, et al. Vitamin B-6 Prevents Heart Failure with Preserved Ejection Fraction Through Downstream of Kinase 3 in a Mouse Model. J Nutr. 2024;154:3031. 10.1016/j.tjnut.2024.08.006
- Xu W, Cao Y, Stephens SB, Arredondo MJ, Chen Y, et al. Folate as a potential treatment for lethal ventricular arrhythmias in TANGO2-deficiency disorder. JCI Insight. 2024;9. 10.1172/jci.insight.171005
- Morimoto J, Satogami K, Naraoka T, Taruya A, Tanaka A. Long-Term Maintenance of Normal Serum Vitamin B Levels Is Associated with Better Outcomes in Patients with Heart Failure. Int Heart J. 2024;65:458. 10.1536/ihj.23-550
